Table 3 Distribution of IL-12A rs568408, IL-12A rs2243115, and IL-12B rs3212227 allelic frequencies among asthmatic patients and comparison individuals.
From: Association of Interleukin-12A rs568408 with Susceptibility to Asthma in Taiwan
Allele | Cases (2 N = 396) | Controls (2 N = 906) | P-value | OR (95%CI) | aOR (95%CI) | ||
|---|---|---|---|---|---|---|---|
n | % | n | % | ||||
IL-12A rs568408 | |||||||
Allele G | 317 | 80.1% | 786 | 86.8% | 1.00 (reference) | 1.00 (reference) | |
Allele A | 79 | 19.9% | 120 | 13.2% | 0.0021* | 1.63 (1.19–2.23) | 1.64 (1.20–2.25) |
IL-12A rs2243115 | |||||||
Allele T | 366 | 92.4% | 847 | 93.5% | 1.00 (reference) | 1.00 (reference) | |
Allele G | 30 | 7.6% | 59 | 6.5% | 0.4845 | 1.18 (0.75–1.86) | 1.18 (0.74–1.86) |
IL-12B rs3212227 | |||||||
Allele A | 223 | 56.3% | 512 | 56.5% | 1.00 (reference) | 1.00 (reference) | |
Allele C | 173 | 43.7% | 394 | 43.5% | 0.9469 | 1.00 (0.80–1.28) | 1.01 (0.79–1.28) |
