Figure 3
From: Topical Fibronectin Improves Wound Healing of Irradiated Skin
(A) Flow diagram for experimental methodology. (B) qRT-PCR demonstrating that fibronectin expression is significantly downregulated after radiation of mouse skin 4–6 weeks after exposure. (C) Irradiated skin heals significantly slower than normal skin at all time points (p < 0.05). (D) Representative normal (top) and irradiated (bottom) wounds at days 0, 12, and 24 post-wounding. (E) Topical application of fibronectin at the time of wounding is associated with significantly accelerated wound healing at all time points (p < 0.05). (F) Representative radiated wounds with vehicle control (top) and fibronectin treatment (bottom) at days 0, 14, and 21.
