Figure 7
From: Structural Characterization of the SMRT Corepressor Interacting with Histone Deacetylase 7

HDAC7 binding to SMRT(1255–1452) alanine mutants. (a,b) Isothermal titration calorimetry data of the HDAC7 interaction with the wild-type SMRT(1255–1452) construct (a) and the SMRT(1255–1452) R1369A mutant (b). (c) Western blot of pull-down assay testing HDAC7 binding of the wild-type SMRT(1358–1391) GST fusion peptide as well as its mutants R1369A, R1381A and the double mutant R1369A/R1381A.