Figure 6

Schematic representations of transcytosis of multifunctional vinblastine liposomes across the BBB and elimination of brain glioma and glioma stem cells. (A) Multifunctional vinblastine liposomes are transported across the blood-brain barrier, enter brain glioma or glioma stem cells, and are distributed throughout the cells. (B) The signaling pathways for necrosis, apoptosis and autophagy in brain glioma or glioma stem cells are triggered by multifunctional vinblastine liposomes.