Table 1 Molecular weights and critical micelle concentrations (CMCs) of TMGs (TMG-As/Ts) and a conventional detergent (DDM) and hydrodynamic radii (R h; n = 5) of their micelles measured in pure water.
From: Tandem malonate-based glucosides (TMGs) for membrane protein structural studies
Detergent | M.W.a | CMC (mM) | CMC (wt%) | R h (nm)b |
|---|---|---|---|---|
TMG-A11 | 1149.41 | ~0.015 | ~0.0017 | 3.1 ± 0.15 |
TMG-A12 | 1177.47 | ~0.010 | ~0.0012 | 3.3 ± 0.09 |
TMG-A13 | 1205.52 | ~0.006 | ~0.0007 | 3.6 ± 0.16 |
TMG-A14 | 1233.58 | ~0.004 | ~0.0005 | 3.8 ± 0.10 |
TMG-T11 | 1227.50 | ~0.020 | ~0.0025 | 3.0 ± 0.07 |
TMG-T12 | 1255.55 | ~0.015 | ~0.0019 | 3.1 ± 0.06 |
TMG-T13 | 1283.61 | ~0.006 | ~0.0008 | 3.3 ± 0.08 |
TMG-T14 | 1311.66 | ~0.004 | ~0.0005 | 3.8 ± 0.09 |
DDM | 510.1 | ~0.17 | ~0.0087 | 3.4 ± 0.03 |
