Figure 6 | Scientific Reports

Figure 6

From: Bone morphogenetic protein 4 promotes the survival and preserves the structure of flow-sorted Bhlhb5+ cochlear spiral ganglion neurons in vitro

Figure 6

BMP4 treatment influenced the growth of the growth cone in SGN explants: (A) The protocol for the experiment. (B and C) Low and high-magnification immunofluorescence images showing the morphological characteristics of the SGN growth cone after culture with and without BMP4. Phalloidin staining is in red and Tuj1 staining is in green. (D) The average number of filopodia per growth cone increased significantly after BMP4 treatment. (E) Quantification of the average length of the filopodia. (F) The average area of the growth cone. *p < 0.05. Scale bars are 1 μm in (B and C).

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