Table 1 Pathways identified by DGAT-path as significantly associated with SCZ and Breast cancer.
Pathway ID | Pathway Name | P-value |
|---|---|---|
SCZ | ||
GO:0007156 | Homophilic cell adhesion | <10−6 |
GO:0007628 | Adult walking behavior | <10−6 |
GO:0014069 | Postsynaptic density | <10−6 |
GO:0045211 | Postsynaptic membrane | <10−6 |
GO:0046415 | Urate metabolic process | <10−6 |
path:hsa04713 | Circadian entrainment | <10−6 |
path:hsa04724 | Glutamatergic synapse | <10−6 |
path:hsa04730 | Long-term depression | <10−6 |
GO:0005245 | Voltage-gated calcium channel activity | 1.9 × 10−6 |
P00019 | Endothelin signaling pathway | 1.9 × 10−6 |
REACT_18325 | Regulation of insulin secretion | 1.9 × 10−6 |
GO:0044325 | Ion channel binding | 3.0 × 10−6 |
path:hsa04270 | Vascular smooth muscle contraction | 6.9 × 10−6 |
GO:0007169 | Transmembrane receptor protein tyrosine kinase signaling pathway | 6.9 × 10−6 |
path:hsa04720 | Long-term potentiation | 6.9 × 10−6 |
P00057 | Wnt signaling pathway | 7.9 × 10−6 |
path:hsa04261 | Adrenergic signaling in cardiomyocytes | 8.9 × 10−6 |
Breast Cancer | ||
GO:0002456 | T cell mediated immunity | <9.9. × 10−7 |
GO:0003964 | RNA-directed DNA polymerase activity | <9.9 × 10−7 |
GO:0005751 | Mitochondrial respiratory chain complex IV | <9.9 × 10−7 |
GO:0007506 | Gonadal mesoderm development | <9.9 × 10−7 |
GO:0019031 | Yiral envelope | <9.9 × 10−7 |
GO:0042287 | MHC protein binding | <9.9 × 10−7 |
GO:0042989 | Sequestering of actin monomers | <9.9 × 10−7 |
GO:0050658 | RNA transport | <9.9 × 10−7 |
GO:0070544 | Histone H3-K36 demethylation | <9.9 × 10−7 |
P00012 | Cadherin signaling pathway | <9.9 × 10−7 |
GO:0045211 | Postsynaptic membrane | <9.9 × 10−7 |
GO:0045296 | Cadherin binding | 4.0 × 10−6 |
