Figure 3
From: Improved Growth Patterns in Cystic Fibrosis Mice after Loss of Histone Deacetylase 6
Improved growth phenotype in CF after loss of HDAC6. (a,b) Lengths of 8–10 week old wild-type (WT), F508del (CF), Hdac6−/− (HDA), and F508del/Hdac6−/− (CF/HDA) (a) male mice and (b) female mice (*p = 0.001 for CF vs. all other groups; no other comparisons are significant (p > 0.05); 1-way ANOVA with post-hoc Newman-Keuls test; n = 5–11 mice). (c,d) Weight curves of 8–10 week old WT, CF, HDA, and CF/HDA (a) male and (b) female mice (*p < 0.05 for WT v CF/HDA; ^p < 0.05 for CF v CF/HDA; n = 12–48 mice for days 0–40; n = 6 for days 40+). Data represent the means ± standard deviation.
