Table 3 A summary of hazard ratios (HRs) for subgroup analyses of PD-L1 expression of glioma patients.
From: The prognostic significance of PD-L1 expression in patients with glioma: A meta-analysis
Subgroup analysis | No. of studies | No. of patients | Model | Pooled HR (95% CI) | p value | Heterogeneity (I2) | P value | Subgroup diffrence P value |
|---|---|---|---|---|---|---|---|---|
Patients | — | |||||||
GBM | 5 | 823 | Random | 1.40 (1.03–1.90) | 0.030 | 65.5% | 0.021 | |
Index | 0.530 | |||||||
Protien | 4 | 457 | Random | 1.43 (0.97–2.10) | 0.068 | 60.7% | 0.054 | |
Gene | 2 | 595 | Random | 1.20 (0.83–1.74) | 0.322 | 67.7% | 0.079 | |
Cut off | — | |||||||
Percentage (≥5%) | 3 | 440 | Fixed | 1.24 (0.99–1.54) | 0.061 | 33.5% | 0.222 | |
Analytical method | 0.530 | |||||||
Univariate | 4 | 457 | Random | 1.43 (0.97–2.10) | 0.068 | 60.7% | 0.054 | |
Multivariate | 2 | 595 | Random | 1.20 (0.83–1.74) | 0.322 | 67.7% | 0.079 | |
