Table 1 Characteristics of patients with or without new onset ischemic lower-extremity peripheral artery disease during follow-up.

From: Electronegative low-density lipoprotein increases the risk of ischemic lower-extremity peripheral artery disease in uremia patients on maintenance hemodialysis

Variable

PAD (−) (n = 68)

PAD (+) (n = 22)

P value

Age (years)

52.5 (44.2–61.0)

59.5 (56.2–63.0)

0.015

Sex (male) (%)

84.3%

70.7%

0.15

HD Vintage (months)

51.0 (37.3–67.8)

42.0 (31.3–67.3)

0.17

BMI (kg/m2)

22.2 (21.2–24.0)

22.7 (21.3–26.0)

0.29

IHD (%)

29.4%

68.1%

<0.001

Hypertension (%)

76.4%

95.4%

0.06

DM (%)

10.3%

50.0%

0.001

Smoking (%)

13.2%

4.5%

0.44

Triglyceride (mg/dl)

134 (98–199)

256 (199–345)

<0.001

Cholesterol (mg/dl)

176 (150–192)

212 (176–224)

<0.001

HDL-C (mg/dl)

39 (34–44)

39 (31–48)

0.88

LDL-C (mg/dl)

98 (78–115)

111 (90–149)

0.021

L5%

1.13 (0.90–1.83)

3.03 (2.36–4.54)

<0.001

Hs-CRP (mg/dl)

0.34 (0.16–0.75)

1.18 (0.79–2.07)

<0.001

Calcium (mg/dl)

9.5 (9.1–10.1)

9.6 (9.2–10.2)

0.58

Phosphate (mg/dl)

5.2 (4.4–5.9)

5.6 (4.6–6.1)

0.22

Ca × P

49.2 (43.2–56.7)

52.5 (43.1–60.7)

0.33

iPTH (pg/mL)

198 (153–300)

247 (177–297)

0.35

BUN (mg/dl)

64.5 (58.2–72.5)

67.0 (56.2–75.2)

0.84

Creatinine (mg/dl)

10.2 (9.7–11.4)

10.8 (10.1–11.4)

0.46

  1. Data are presented as the median value (interquartile range) or as the percentage. BMI = body mass index; BUN = blood urea nitrogen; Ca × P, calcium-phosphorous product; DM = diabetes mellitus; HD = hemodialysis; HDL-C = high-density lipoprotein-cholesterol; Hs-CRP = high sensitivity-C reactive protein; IHD = ischemic heart disease; iPTH = intact parathyroid hormone; LDL-C = low-density lipoprotein-cholesterol.
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