Figure 7 | Scientific Reports

Figure 7

From: Coordination of Bactericidal and Iron Regulatory Functions of Hepcidin in Innate Antimicrobial Immunity in a Zebrafish Model

Figure 7

Co-evolution analysis of hepcidin and Fpn genes in vertebrates. (A and B) The 50% majority-rule consensus tree from Bayesian inference (BI) of conserved functional region of hepcidin (A) and Fpn (B) homologs among vertebrates were built, and each was divided into 3 clades based on the homologous relationship. The number above the branches indicates the statistical support value, while the scale bar indicates the number of substitutions per site and lineage-specific ω = Ka/Ks ratios for particular branches calculated by PAML. (C) The correlation coefficient of the relationship between hepcidin propeptide (or mature peptide) and Fpn (or Fpn-HBD).

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