Figure 3
From: A novel protein kinase inhibitor IMB-YH-8 with anti-tuberculosis activity
The predicted mode of IMB-YH-8 binding to PknB. (a) Superimposition of the predicted binding mode of mitoxantrone (in stick, carbon in orange) in the context of the crystal structure (in stick, carbon in grey). (b) The detailed interactions between IMB-YH-8 and PknB. (c) The alignment between the binding mode of IMB-YH-8 (in stick, carbon in orange) and MIX (in stick, carbon in grey). The receptor: hydrogen bond is indicated by the blue line with arrow.
