Table 1 Micro-CT analysis of OA femoral head subchondral bone samples from Normal-weight (NW, n = 6) and over-weight/obese (OW/OB, n = 6) patient cohorts.

From: Resistin promotes the abnormal Type I collagen phenotype of subchondral bone in obese patients with end stage hip osteoarthritis

Parameter

NW

OW/OB

p value

Gender (M:F)

3:3

3:3

—

Age (yr)

59 ± 10

57 ± 9

0.749

BMI

23.5 ± 1.1

33.5 ± 2.5

0.007

W:H ratio

0.87 ± 0.07

0.91 ± 0.08

0.303

Body Fat %

23.9 ± 7.3

38.1 ± 7.5

0.008

BV/TV

0.42 ± 0.04

0.43 ± 0.12

0.85

Tb.Th

0.34 ± 0.03

0.27 ± 0.04

0.01

Tb.N

1.25 ± 0.12

1.66 ± 0.62

0.14

Tb.Sp

0.47 ± 0.08

0.41 ± 0.25

0.61

BS/BV

5.91 ± 0.54

7.53 ± 1.14

0.01

SMI

−0.27 ± 0.5

−0.4 ± 0.95

0.76

DA

1.55 ± 0.1

1.45 ± 0.2

0.31

EF

−0.40 ± 0.14

−0.43 ± 0.22

0.16

  1. Patient samples were excluded if a bone cyst was present within the 1 cm3 section of femoral head scanned. BV/TV = Bone volume/Total volume; TB.Th = Trabecular thickness; TB.N = trabecular number; TB.Sp. = trabecular separation; BS/BV = Bone surface/Bone volume; SMI = Structure Model Index; DA = Degree of Anistrophy, EF = Ellipsoid factor. Data expressed as mean ± SD.
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