Figure 2
From: Down-regulation of KCa2.3 channels causes erectile dysfunction in mice
Immunolocalization for KCa2.3 channels in wild type (WT) mouse corpus cavernosum. (A) Histological image of penile tissue from a WT mouse. The square area represents part of the corpus cavernosum. The corpus cavernosum is surrounded by the albuginea layer (asterisks) and skeletal muscle. Arrows indicate KCa2.3 labeling in capillaries between the skeletal muscle fibers. (B) Histological image showing an enlargement of the square area representing the corpus cavernosum from panel A. KCa2.3 immunoreactivity is seen in blood vessels of the corpus cavernosum (inset C and D). (C) KCa2.3 expression in the apical plasma membrane domains of endothelial cells of a small helicine artery in the corpus cavernosum (arrows, enlargement of inset C). (D) Similar KCa2.3 expression in the apical plasma membrane domains of endothelial cells of a probable larger artery in corpus cavernosum (arrows, enlargement of inset D).
