Table 1 Change in test set performance of the same ligand-centric target prediction method depending on the employed knowledge-base.

From: Predicting the Reliability of Drug-target Interaction Predictions with Maximum Coverage of Target Space

Method

avNPT

avACC

avPR

avRC

avMCC

avTN

avFP

avFN

avTP

Peon et al.7

7.9

0.996

0.296

0.403

0.300

3016.8

5.9

6.3

2.0

This paper

11.4

0.996

0.311

0.384

0.305

4186.1

8.4

8.5

3.0

  1. The expanded knowledge-base can be found in the last row.
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