Table 2 Characteristics of the infants examined in this study.

From: Late-onset Circulatory Collapse and Continuous Positive Airway Pressure are Useful Predictors of Treatment-requiring Retinopathy of Prematurity: A 9-year Retrospective Analysis

 

Total (n = 418)

TR-ROP (n = 76)

Mild ROP (n = 119)

No ROP (n = 223)

P-value

PMA of ROP maturation, mean (SD), week

35.5 (2.3)

35.6 (2.7)

0.68*

Predictive factors

  Baseline

    GA, mean (SD), week

28.8 (3.0)

24.8 (1.6)

27.7 (2.3)

30.8 (1.8)

<0.0001

    BW, mean (SD), g

1134 (453)

636 (206)

929 (291)

1414 (375)

<0.0001

    Male, No. (%)

221 (53)

44 (58)

63 (53)

115 (52)

0.75

  Circulatory function

    LCC, No. (%)

95 (23)

50 (66)

34 (29)

11 (5)

<0.0001

    Sepsis, No. (%)

36 (9)

20 (26)

9 (8)

7 (3)

<0.0001

    PDA ligation, No. (%)

42 (10)

20 (26)

15 (13)

7 (3)

<0.0001

    Transfusion, No. (%)

130 (31)

62 (82)

45 (38)

23 (10)

<0.0001

  Pulmonary function

    Use history of oxygen, No. (%)

309 (74)

75 (99)

108 (91)

126 (57)

<0.0001

    CPAP, No. (%)

138 (33)

56 (74)

39 (33)

43 (19)

<0.0001

    BPD, No. (%)

120 (29)

60 (79)

41 (34)

19 (9)

<0.0001

  Circulation in CNS

    IVH, No. (%)

62 (15)

25 (33)

26 (22)

11 (5)

<0.0001

    PVL, No. (%)

23 (6)

8 (11)

8 (7)

7 (3)

0.048

  Growth

    Weight gain at 6 weeks after birth, mean (SD), g

443 (278)

227 (137)

374 (195)

593 (292)

<0.0001

    Weight gain rate, mean (SD), g/day

10.5 (10.5)

3.1 (7.4)

6.5 (9.4)

15.0 (9.7)

<0.0001

  1. Abbreviations: ROP, retinopathy of prematurity; TR-ROP, treatment-requiring retinopathy of prematurity; PMA, postmenstrual age; GA, gestational age; SD, standard deviation; BW, birthweight; LCC, late-onset circulatory collapse; PDA, patent ductus arteriosus; CPAP, continuous positive airway pressure; PMA, postmenstrual age; BPD, bronchopulmonary dysplasia; CNS, central nervous systems; IVH, intraventricular hemorrhage; PVL, periventricular leukomalacia. *Unpaired Student’s t-test; Wilcoxon rank sum test; chi-squared test.