Figure 1 | Scientific Reports

Figure 1

From: Knockout of the peroxiredoxin 5 homologue PFAOP does not affect the artemisinin susceptibility of Plasmodium falciparum

Figure 1

Chemical structures of artemisinin derivatives and QTL analysis. (a) Chemical structures of compounds indicated. (b) In vitro ART and ATM IC50 values of 32 F1 progeny from the 7G8 × GB4 cross and the two parental clones (indicated by arrows). Means ± SEM of at least five independent determinations. (c) QTL analysis. The logarithm of odds (LOD) scores are shown for ART (black lines) and ATM (grey lines) responses as a function of genomic location. Loci associated with decreased ART and ATM susceptibility are indicated. The dotted line represents the confidence line with p < 0.01.

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