Table 2 mRNA expression of inflammatory genes in insulin-responsive tissues: adipose tissue, liver and skeletal muscle from mice fed the control diet (2) or obesogenic diets: high-sugar (HS), high-fat (HF) and high-sugar/high-fat diet (HSHF) for eight weeks.
Tissue | mRNA | CD | HS | HF | HSHF |
|---|---|---|---|---|---|
eAT | F4/80 | 1 ± 0.09 | 2.5 ± 0.36 | 4.5 ± 0.81 | 5.7 ± 1.42a |
Adiponectin | 1.4 ± 0.21 | 1.1 ± 0.28 | 0.5 ± 0.10a | 0.5 ± 0.18a | |
Leptin | 1.2 ± 0.15 | 3.9 ± 0.40a | 3.0 ± 0.37a | 2.4 ± 0.35b | |
Liver | Collagen | 1.1 ± 0.23 | 2.2 ± 0.37a | 1.3 ± 0.28 | 1.6 ± 0.17 |
Tnf-α | 1.5 ± 0.41 | 2.9 ± 0.87c | 0.7 ± 0.14 | 1.1 ± 0.27 | |
Soleus Muscle | Leptin | 1.1 ± 0.25 | 0.3 ± 0.07a,c | 1.4 ± 0.17 | 1.1 ± 0.26 |
Tlr4 | 1.0 ± 0.11 | 1.3 ± 0.13 | 1 ± 0.13 | 1.6 ± 0.09a,c |