Figure 5
A subset of Prime Motif matching nucleotides have been aligned to the IGHV3-53 germline sequence. The visualized segment of the resulting multiple alignment corresponds with the FR3 region of the antibody sequence. All other lines contain subsequences obtained from Prime Motif matching antibodies. Insertions and deletions in the multiple alignment are highlighted in red. A single adenine insertion is present in all sequences within the input nucleotide subset. The insertion is followed by a single deletion that occurs within the space of 24 nucleotides.
