Figure 5
From: Modifying Dendritic Cell Activation with Plasmonic Nano Vectors
PNVs caused a down-regulation of the endocytic DEC-205 receptor and an up-regulation of the CD40 receptor. DCs were treated with 1, 10, and 50 μg/ml of PNVs or LPS (5 μg/ml) as a positive control, and flow cytometry was performed for (a) DEC-205 and (b) CD40 receptor expression. Day 0 (D 0) = untreated controls, black filled bars, Day 3 (D 3) = white non-filled bars, and Day 7 (D 7) = gray filled bars. These experiments are a compilation of 3 independent experiments; n = 3 per group.
