Figure 3
From: 0404 inhibits hepatocellular carcinoma through a p53/miR-34a/SIRT1 positive feedback loop
0404 inhibited hepatocellular tumor growth in vivo. (A) Luciferase emission showed that 0404 inhibited the tumor growth in vivo. (B and C) 0404 significantly inhibited the tumor volume and weight excised from nude mice at day 25. (D) p53 levels were up-regulated in the HepG2 tumors excised from nude mice after treatment with 0404. (E) TUNEL assay was used to detect the cell apoptosis in the HepG2 tumors excised from nude mice after treatment with 0404.
