Figure 1

Screening of optimal peptides. (A) Flow chart for peptide screening via bioinformatics and cell-based assays. (B) Simulated image of VEGFR-1 interacting with the binding core of VEGF125-136. (C) In vitro competitive binding of the 13 selected peptides with 125I-VEGF165 and the 3H-TDR incorporation assays. (D) Structures of the HYNIC- and EC-conjugated peptides.