Table 1 Biochemical Parameters of Serum and Livera.
From: Herbal medicine Yinchenhaotang protects against α-naphthylisothiocyanate-induced cholestasis in rats
Parameters | Normal | 8w Model | 12w Model | YCHT-treated |
|---|---|---|---|---|
n | 8 | 10 | 12 | 10 |
Body weight (g, mean ± SD) | 474.5 ± 57.24 | 349.3 ± 25.13** | 396.2 ± 32.46**## | 380.7 ± 19.70 |
Liver weight (g, mean ± SD) | 12.65 ± 2.27 | 13.56 ± 1.39 | 13.91 ± 1.26 | 14.43 ± 0.96 |
Liver/body weight ratio (%) | 2.6 ± 0.2 | 3.8 ± 0.2** | 3.5 ± 0.1**# | 3.8 ± 0.2† |
ALT (IU/L) | 71.38 ± 19.99 | 137.6 ± 85.49 | 205.6 ± 81.91**# | 78.86 ± 23.25†† |
AST (IU/L) | 144.8 ± 24.74 | 181.7 ± 143.2 | 266.5 ± 88.6*# | 141.7 ± 35.4† |
ALB (g/L) | 30.05 ± 4.6 | 26.12 ± 2.74* | 28.54 ± 4.34* | 31.19 ± 3.17† |
ALP (IU/L) | 85.38 ± 16.40 | 154.30 ± 49.18** | 136.90 ± 33.04** | 118.40 ± 39.54† |
TBIL (μmol/L) | 1.60 ± 0.44 | 4.21 ± 2.62* | 6.92 ± 3.11**## | 3.00 ± 1.19†† |
DBIL (μmol/L) | 0.80 ± 0.39 | 3.27 ± 2.35** | 5.49 ± 2.80**## | 2.11 ± 0.83†† |
TG (mmol/L) | 0.98 ± 0.33 | 0.47 ± 0.06** | 0.58 ± 0.08** | 0.47 ± 0.12 |
TC (mmol/L) | 2.41 ± 0.57 | 2.51 ± 0.36 | 2.84 ± 0.27** | 2.44 ± 0.37† |
Cr (μmol/L) | 42.38 ± 9.07 | 42.50 ± 5.64 | 46.91 ± 8.71 | 41.00 ± 7.77 |
BUN (mmol/L) | 5.73 ± 0.85 | 4.13 ± 0.76** | 5.67 ± 0.63## | 5.94 ± 1.66 |
γ-GT (U/L) | 9.84 ± 3.407 | 30.75 ± 4.06** | 46.37 ± 5.518**# | 32.16 ± 1.697†† |
HYP (μg/g liver tissue) | 234.5 ± 13.1 | 460.2 ± 33.21** | 641.7 ± 77.81**## | 470.4 ± 36.68† |
