Figure 5 | Scientific Reports

Figure 5

From: IGF1R deficiency attenuates acute inflammatory response in a bleomycin-induced lung injury mouse model

Figure 5

Diminished cell proliferation in IGF1R-deficient lungs after BLM challenge. (a) Representative images of Ki67 immuno-staining (in brown, orange arrows) under the pulmonary artery (top) and in the alveolar parenchyma (bottom), and (b) quantification of cell proliferation rates (Ki67+) in BLM treated UBC-CreERT2; Igf1r fl/fl (CreERT2) vs. Igf1r fl/fl lungs at D3 (scale bar: 20 μm). Numbers within graphic bars indicate the number of mice analyzed and data are expressed as mean ± SEM. **p < 0.01 (Mann-Whitney U test). PV, perivascular; pa, pulmonary artery.

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