Figure 6
From: Attenuation of Innate Immunity by Andrographolide Derivatives Through NF-κB Signaling Pathway
Effects of andrographolide derivatives on class A CpG ODN2216-stimulated TLR9 signaling. AD-293 cells were stimulated with ODN2216 alone or combined with andrographolide derivatives. The mRNA levels of TNF-α and IFN-β treated with (A) and (B) 3b and 5a, or (C) and (D) 3a, 5b, and 6b, respectively, were quantitated by real-time PCR. The results are representative of at least three independent experiments and presented as mean ± SD (**p < 0.05; n.s., nonspecific).
