Figure 3 | Scientific Reports

Figure 3

From: Label Free Detection of Sensitive Mid-Infrared Biomarkers of Glomerulonephritis in Urine Using Fourier Transform Infrared Spectroscopy

Figure 3

Five features of interest identified in experimental glomerulonephritis. (a) The average normalized second derivative FTIR spectra of urine obtained from normal WKY rats and different stages of NTN rats. (b) Peaks of interest (1668 cm−1, 1545 cm−1, 1242 cm−1, 1107 cm−1, and 1033 cm−1) potentially relevant to renal inflammation and/or fibrosis. (c) The PCA bioplot displays the correlations between the five spectral markers and individual urine sample of normal rats (n = 34) and d28 NTN rats (n = 18, there was one outlier excluded from this group). PC1 and PC2 explained 75.7% of total variance.

Back to article page