Figure 3 | Scientific Reports

Figure 3

From: Inhibition of highly pathogenic avian influenza (HPAI) virus by a peptide derived from vFLIP through its direct destabilization of viruses

Figure 3

In vivo virucidal effect of the TAT-Kα2 peptide against HPAI (H5N1). The mice were inoculated with the W149 virus alone or mixtures of the W149 virus and each peptide (TAT-Kα2 or TAT-scramble peptides), and (a) percent body weight and (b) survival percentage were monitored for 15 days. (c) The lung virus titers of each group (three randomly selected mice from each group were sacrificed) are expressed as the means ± SD of the log10 plaque-forming units (PFU) per 0.1 g of tissue. The closed bar indicates the virus titer at 3 DPI, and the open bar indicates the virus titer at 5 DPI. (d) Histopathologic observation at 5 DPI. The upper panels were observed by light microscopy at 40× magnification, and the lower panels were observed at 200× magnification.

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