Figure 5 | Scientific Reports

Figure 5

From: Inhibition of highly pathogenic avian influenza (HPAI) virus by a peptide derived from vFLIP through its direct destabilization of viruses

Figure 5

Screening for critical amino acid (aa) residues in the TAT-Kα2 peptide that are responsible for its virucidal effect. As listed in Table 1, TAT-scramble, TAT-Kα2, and four different alanine mutant (M, M1, M2 and M3) peptides were compared to identify the critical aa residues that were responsible for the antiviral ability. (a) Infectivity of the PR8-GFP virus after treatment with each peptide (40 μM). The upper panels show the fluorescence microscopy observations and the lower panels show the light microscopy observations at 200× magnification. (b) Virus titers after treatment with each peptide. Virus titers are expressed as the means ± SD of 103 PFU/ml.

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