Figure 2
From: Serial femtosecond crystallography structure of cytochrome c oxidase at room temperature
Room-temperature SFX structure of ba 3 CcO. (a) Overall structure with subunit I in green, subunit II in blue, subunit IIa in pink, heme groups in black, copper ions in purple and lipids in orange. (b) Close-up view of the proton pathway where the SFX structure is shown in green/blue/pink and the cryo-LCP structure (PDB code 3S8G) is shown in grey. Water molecules are shown in red (SFX) and grey (cryo-LCP). (c) Close-up view of the area around the presumed proton-loading site. The SFX structure is shown in green/blue and the bovine heart aa 3-type CcO (PDB code 3WG7) in grey. The magnesium ion of the bovine heart structure is shown in brown. Water molecules are shown in red (SFX) and grey (bovine heart). Heme a 3 is shown in black (SFX) and grey (bovine heart). The amino acid numbering refers to the ba 3 CcO.
