Figure 4 | Scientific Reports

Figure 4

From: Der f 31, a novel allergen from Dermatophagoides farinae, activates epithelial cells and enhances lung-resident group 2 innate lymphoid cells

Figure 4

Airway allergy is induced by Der f 31. Four- to 7-week-old female BALB/c mice were immunized with PBS, Der f 31 or Der f 1 and then challenged with Der f 31 or Der f 1 for one week. (A) The scheme of establishment of mouse model. (B) Total IgE, allergen-specific IgE, IgG1 and IgG2a were detected by ELISA by optical density (OD). (C) The cytokines in BALF. (D) The cytokines in the lung homogenates. E, Histological sections of lung tissues. These data (means ± SEMs) were generated from one of three experiments (n = 6) and processed with GraphPad software. The significant differences between two groups were tested by two-tailed T-test. **p < 0.01. ***p < 0.001. ns, no significant difference.

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