Figure 5
Disruption of active myosin II distribution induced the collapse of leading front and inhibited migration of astrocyte-like OECs. (A–B) Images of migrating astrocyte-like type 1 OECs before and after the frontal application of a gradient of DMSO as a control (A), or ML-7 (5 mM in micropipette, B). (C–D) Images of migrating astrocyte-like type 2 OECs before and after the frontal application of a gradient of DMSO as a control (C), or ML-7 (5 mM in micropipette, D). (E) Histogram showing the percentages of collapsed and reversed OECs in total cells after application ML-7. Time, min, scale bar, 20 μm.
