Figure 2
From: Probing the missing mature β-cell proteomic landscape in differentiating patient iPSC-derived cells
Cellular heterogeneity. (a) Co-expression of glucagon (green) and insulin (red) in S7 cells (arrows). (b) Insulin+ S7 cells (red) positive (arrows) or negative (arrowhead) for NKX6.1 transcription factor (green). (c) Relative abundance (log2) of non-β endocrine islet cells markers in S7 cells compared to all the ten samples of a TMT 10-plex as further explained in Methods. Scale bar: 25 µm.
