Table 2 Clinicopathological status of breast cancer and immunohistochemical staining (IHC).

From: Serum TFF1 and TFF3 but not TFF2 are higher in women with breast cancer than in women without breast cancer

Characteristic

Total

TFF1

TFF1 P value

TFF3

TFF3 P value

Age (years, mean ± SD)

54 ± 12.3

    

Sex

  Women

46

    

Histological type

  

0.456

 

0.614

  DCIS

5

1.8 ± 0.8

 

2.4 ± 0.9

 

  IDC

35

1.3 ± 1.0

 

2.0 ± 1.0

 

  Others

6

1.7 ± 1.0

 

2.3 ± 1.0

 

Tumor size

  

0.534

 

0.793

  >2 cm

17

1.5 ± 0.9

 

2.1 ± 1.0

 

  ≤2 cm

29

1.3 ± 1.0

 

2.1 ± 1.0

 

Nodal status (missing 3)

  

0.102

 

0.904

  pN−

29

1.2 ± 0.8

 

2.1 ± 1.0

 

  pN+

14

1.7 ± 1.1

 

2.1 ± 1.0

 

Nuclear grade (missing 6)

  

0.917

 

0.610

  I

25

1.4 ± 0.9

 

2.0 ± 1.0

 

  II

5

1.2 ± 1.1

 

1.8 ± 1.1

 

  III

10

1.4 ± 1.3

 

2.3 ± 1.1

 

Lymphatic vessel invasion

  

0.305

 

0.205

  Negative

34

1.5 ± 0.9

 

2.0 ± 1.0

 

  Positive

12

1.2 ± 1.1

 

2.4 ± 0.9

 

Vascular invasion

  

0.719

 

0.564

  Negative

34

1.4 ± 0.9

 

2.1 ± 1.0

 

  Positive

12

1.5 ± 1.1

 

2.3 ± 0.9

 

ER (missing 1)

  

0.109

 

0.836

  Negative

6

0.8 ± 0.8

 

2.2 ± 1.0

 

  Positive

39

1.5 ± 1.0

 

2.1 ± 1.0

 

PR (missing 2)

  

0.011

 

0.793

  Negative

7

0.6 ± 0.5

 

2.0 ± 1.3

 

  Positive

37

1.6 ± 1.0

 

2.1 ± 0.9

 

HER2 (missing 6)

  

0.182

 

0.342

  Negative

36

1.4 ± 1.0

 

2.0 ± 1.0

 

  Positive

4

0.8 ± 0.5

 

2.5 ± 1.0

 

Ki67 (missing 7)

  

0.059

 

0.650

  <30%

28

1.5 ± 0.9

 

2.1 ± 1.0

 

  ≥30%

11

1.3 ± 1.0

 

1.9 ± 1.0

 

Subtype (missing 7)

  

0.067

 

0.253

  LuminalA

25

1.7 ± 0.9

 

2.0 ± 1.0

 

  LuminalB

10

1.0 ± 0.9

 

2.0 ± 1.1

 

  HER2 type

2

0.5 ± 0.7

 

3.0 ± 0

 

  Triple negative

2

0.5 ± 0.7

 

1.0 ± 0

 
  1. TFF1 expression was significantly correlated with PR expression only, however, TFF3 expression was not related to any clinicopahological characteristics. SD: Standard Deviation, IDC: Invasive Ductal Carcinoma.