Figure 7

Substrate binding cleft of modelled EcChi1. (A) Aromatic residues lining along the substrate binding cleft (protein in surface representation and aminoacids in green and red sticks) and aminoacids interacting with chitin tetramer labeled in red colour. (B) Docked conformation of chitin tetramer (white sticks) and its possible interactions with residues (green lines) along with catalytic residue, Glu153 (yellow line) of EcChi1. (C) Deep active site cleft of EcChi1 showing catalytic (yellow colour) and aromatic (red colour) amino acids.