Table 1 Characteristics of patients included in the LINE-1 methylation analysis: controls, gastritis, gastric cancer and colorectal cancer patients.
From: LINE-1 hypomethylation is not a common event in preneoplastic stages of gastric carcinogenesis
Total | Â | Gastric cancer | Colorectal cancer | Chronic/atrophic gastritis | Controls |
|---|---|---|---|---|---|
n(%) | n(%) | n(%) | n(%) | ||
n = 80 | n = 24 | n = 37 | n = 19 | ||
Age | mean (SD) | 65.9 (11.7) | 69.3 (8.8) | 57.3 (13.0) | 49.1 (14.9) |
Gender | Female | 33 (41.3) | 11 (45.8) | 25 (67.6) | 12 (63.2) |
Male | 47 (58.7) | 13 (54.2) | 12 (32.4) | 7 (36.8) | |
Tumor localization | Cardia | 8 (10.0) | — | — | — |
Corpus | 44 (55.0) | — | — | — | |
Antrum | 28 (35.0) | — | — | — | |
Proximal colon | — | 9 (37.5) | — | — | |
Distal colon | — | 15 (62.5) | — | — | |
TNM staging | I | 15 (18.7) | 2 (8.3) | — | — |
II | 21 (26.3) | 10 (41.7) | — | — | |
III | 36 (45.0) | 6 (25.0) | — | — | |
IV | 8 (10.0) | 4 (16.7) | — | — | |
Unknown | — | 2 (8.3) | — | — | |
T | 1/2 | 17 (21.3) | 2 (8.3) | — | — |
3 | 36 (45.0) | 18 (75.0) | — | — | |
4 | 27 (33.7) | 1 (4.2) | — | — | |
Unknown | — | 3 (12.5) |  |  | |
N | 0 | 28 (35.0) | 13 (54.2) | — | — |
1 | 15 (18.7) | 7 (29.2) | — | — | |
2 | 13 (16.3) | 2 (8.3) | — | — | |
3 | 22 (27.5) | — | — | — | |
Unknown | 2 (2.5) | 2 (8.3) | Â | Â | |
M | 0 | 72 (90.0) | 8(33.3) | — | — |
1 | 8 (10.0) | 4 (16.6) | — | — | |
Unknown | Â | 12 (50.0) | Â | Â | |
G | 1 and 2 | 31 (38.8) | 18 (75.0) | — | — |
3 | 49 (61.2) | 3 (12.5) | — | — | |
Unknown | — | 3 (12.5) | — | — | |
Lauren’s classification | Diffuse | 44 (55.0) | — | — | — |
Intestinal | 25 (31.3) | — | — | — | |
Mixed | 7 (8.7) | — | — | — | |
Unknown | 4 (5.0) | — | — | — | |
H. pylori infection | Positive | 17 (21.3) | — | 25 (67.6) | — |
Negative | 8 (10.0) | — | 12 (32.4) | 19 (100) | |
Unknown | 55 (68.7) | — | — | — |
