Figure 3

(A) Cysteine bond formation between two adjacent C80 across the rhombohedral channel along the two-fold symmetry axis in the oxidised form of α-TTP S . (B) Comparison of the structures in the proximity of the C-terminus. Monomeric α-TTP (tan); α-TTP S reduced state (pink); α-TTP S oxidised state (cyan). The dashed arrow highlights the large conformational change at the N-terminus (aa’s 1–47) required to expose the trimeric interface.