Figure 6
From: “High-Throughput Characterization of Region-Specific Mitochondrial Function and Morphology”
Mitochondrial membrane potential (Δψ) measurement of C. elegans longevity mutants. (A) Quantification of Δψ (by JC-9 ratio) for various long-lived nematode mutants. Wilcoxon Rank Sum tests were performed against N2 control (Ω = P < 0.00001) or against daf-2 (ѳ = P < 0.00001) strains. (B) Median profiles displaying spatial distribution of JC-9 ratio of C. elegans longevity strains. (C) Significance (log10(P-value)) plots derived from median profiles in (B) comparing each profile to daf-2 nematodes. For significance plots a value ≥ 0 is equivalent to P ≤ 0.05 by Wilcoxon Rank Sum Test. All animals are positioned with the anterior side to the left. Plots are representative of three biological replicates and derived from n ≥ 50 organisms. Sample size (n) for all experiments and exact P-values can be found in the Supplementary Table. L.A. Daniele provided the illustrations.
