Table 1 Comparison of genotype and allele frequencies of CFH, CFHR3 and CFHR5 single nucleotide polymorphisms (SNPs) in patients with rare glomerular nephropathies and control subjects.
From: A haplotype in CFH family genes confers high risk of rare glomerular nephropathies
SNP ID |  | Cases (n = 91) | Controls (n = 300) | P-value* | OR (95% CI) |
|---|---|---|---|---|---|
CFH | |||||
 rs55807605 | |||||
  Allele (%) | A | 4 (2.2) | 10 (1.7) | 0.749 | 1.33 (0.41–4.28) |
G | 178 (97.8) | 590 (98.3) | |||
  Genotype (%) | AA | 0 (0.0) | 0 (0.0) | 0.747a | 1.33 (0.41–4.36) |
AG | 4 (4.4) | 10 (3.3) | |||
GG | 87 (95.6) | 290 (96.7) | |||
CFHR3 | |||||
 rs61737525 | |||||
  Allele (%) | T | 5 (2.7) | 4 (0.7) | 0.036 | 4.21 (1.12–15.84) |
C | 177 (97.3) | 596 (99.3) | |||
  Genotype (%) | TT | 1 (1.1) | 2 (0.7) | 0.028a | 6.85 (1.23–38.03) |
TC | 3 (3.3) | 0 (0.0) | 0.549b | 1.66 (0.15–18.47) | |
CC | 87 (95.6) | 298 (99.3) | |||
CFHR5 | |||||
 rs57960694 | |||||
  Allele (%) | A | 4 (2.2) | 4 (0.7) | 0.090 | 3.35 (0.83–13.52) |
G | 178 (97.8) | 596 (99.3) | |||
  Genotype (%) | AA | 0 (0.0) | 0 (0.0) | 0.089a | 3.40 (0.83–13.89) |
AG | 4 (4.4) | 4 (2.3) | |||
GG | 87 (95.6) | 296 (97.7) | |||
