Table 2 Haplotype analysis for CFH, CFHR3 and CFHR5 single nucleotide polymorphisms (SNPs).

From: A haplotype in CFH family genes confers high risk of rare glomerular nephropathies

SNPs alleles

Haplotype frequency

Association test between rare kidney diseases and controls

rs55807605

rs61737525

rs57960694

Cases (n = 91)

Controls (n = 300)

P-value*

OR (95% CI)

G

C

G

0.973

0.980

0.563

0.72 (0.25–2.08)

A

C

G

0.000

0.010

0.345

1.010 (1.002–1.018)

A

T

A

0.022

0.003

0.029

6.72 (1.22–36.99)

G

T

G

0.005

0.003

0.549

1.65 (0.15–18.32)

A

C

A

0.000

0.003

1.000

1.003 (0.999–1.008)

  1. n = number of subjects; OR = odds ratio; CI = confidence interval.
  2. Individual P values and ORs between cases with rare kidney diseases and controls are provided for the haplotypes
  3. compared with all the other haplotypes. *Fisher’s exact text.
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