Figure 3
From: The production of fibroblast growth factor 23 is controlled by TGF-β2
Effect of TGF-β2 on Fgf23 transcript levels in UMR106 cells is blunted by TGF-β receptor-related kinase inhibitor SB431542. Arithmetic means ± SEM (n = 9) of Fgf23 mRNA abundance (relative to Tbp mRNA) in UMR106 cells incubated without (white bars) or with (black bars) TGF-β2 (10 ng/ml) in the absence or presence of downstream TGF-β receptor-related kinase inhibitor SB431542 (10 μM) for 24 h. ***p < 0.001 indicates significant difference between cells treated with or without TGF-β2. ## p < 0.01 indicates significant difference between cells treated with TGF-β2 alone (2nd bar) and cells treated with TGF-β2 and SB431542 (4th bar) (ANOVA).
