Figure 3
From: Mitsugumin 29 regulates t-tubule architecture in the failing heart
Transgenic expression of Mg29 improves cardiac functional performance in mice lacking MLP protein. (a) Heart weight normalized to body weight (HW/BW), (b) systolic function (dP/dt max), and (c) relaxation (dP/dt min), (d) fractional shortening (FS) percentage, (e) heart rate in beats per minute (BPM), and (f) lung weight normalized to body weight (LW/BW) measured from low-expressing Mg29 DTG mice, tTA-expressing control mice, and Csrp3 −/− mice expressing either Mg29 or tTA. Number of mice analyzed is shown in the bars of each graph. *P < 0.05 versus tTA (control) group. #P < 0.05 versus Mg29 DTG group. §P < 0.05 versus Csrp3 −/−, tTA group. †P < 0.05 versus tTA Csrp3 −/− group by Student’s t-test, although this difference was not quite significant by ANOVA.
