Figure 3
In vivo bioluminescence imaging using Bdnf-Luc Tg mice. The fur on the head of the mouse was shaved before in vivo bioluminescence imaging. The imaging was performed using Bdnf-Luc Tg (a,c) and wild-type (b) mice. Ten minutes after intraperitoneal administration of d-luciferin (150 mg/kg body weight, a,b) or saline (c) under anesthesia, the bioluminescence was measured by in vivo imaging (Exposure: 2 min). The intensity of the bioluminescence signal is shown in pseudocolored images. The photograph of the Tg or wild-type mouse (indicated by (#)) was merged with the pseudocolored image. Scale bar = 20 mm. The experiment was performed independently at least four times, and the same tendency was observed.
