Figure 4
Comparison of the bioluminescence signal obtained by d-luciferin and that by an analogue of d-luciferin, TokeOni. The bioluminescence was first measured using d-luciferin (a). Three hours after the measurement, the bioluminescence was re-measured using TokeOni (b). These substrates were administered to the Tg mice intraperitoneally at the same dose (150 mg/kg body weight) and under the same conditions (Exposure: 2 min). The photograph of the head region of the Tg mouse (indicated by (#)) was merged with the pseudocolored image. Scale bar = 20 mm. The experiment was performed independently at least three times, and the same tendency was observed.
