Figure 6 | Scientific Reports

Figure 6

From: A novel STK1-targeted small-molecule as an “antibiotic resistance breaker” against multidrug-resistant Staphylococcus aureus

Figure 6The alternative text for this image may have been generated using AI.

Inh2-B1 disrupts the formation S. aureus biofilms. (A) Biofilms formation by S. aureus MW2 wild-type, MW2ΔSTK1 and MW2ΔSTP1 mutant strains in the absence and presence of 25 µM Inh2-B1 after 48 h. (B) Effect of Inh2-B1 (25 µM) on the preformed biofilms by S. aureus MW2 wild-type, MW2ΔSTK1, and MW2ΔSTP1 mutant strains. Biofilm formation was quantitatively estimated after 48 h of incubation by the crystal violet staining method. Bar diagrams represent average values (Mean ± S.D) obtained for different parameters from three independent cultures each with three technical replicates. P < 0.05 was treated as a significant difference.

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