Figure 3 | Scientific Reports

Figure 3

From: A Novel Dual Eigen-Analysis of Mouse Multi-Tissues’ Expression Profiles Unveils New Perspectives into Type 2 Diabetes

Figure 3

The sorted loadings of the top sample eigenvectors from the adipose and the pancreas and their interpretations. (A) The adipose top sample eigenvector \({{\rm{v}}}_{1}\) were highly correlated with the age factor, and after week 9 its correlation with the diet factor becomes more significant. (B) The pancreatic first eigenvector \({{\rm{v}}}_{1}\) from the SVD of all RC and HFD samples. Most RC samples were at the top half whereas most HFD samples were at the bottom half. It indicates that the pancreatic first eigen-component reflected predominantly the HFD impact. (C) The sorted loading of the pancreatic second eigenvector from the SVD of all RC and HFD samples. (D) Derived from (C) by keeping only RC samples. (E) When SVD was carried out only for the RC pancreatic samples, the sorted loadings of its first sample eigenvector displayed a chronological order. The exact consistency between (D) and (E) indicates that the pancreatic second eigen-component reflected predominantly the pancreatic development over time.

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