Figure 2 | Scientific Reports

Figure 2

From: The alkaloids of Banisteriopsis caapi, the plant source of the Amazonian hallucinogen Ayahuasca, stimulate adult neurogenesis in vitro

Figure 2

Effects of ayahuasca β-carboline alkaloids on adult neurosphere formation. (a) Representative phase-contrast micrographs showing the number and size of neurospheres after 7 days in culture in the presence of each of the four alkaloids tested (1 µM). The number and diameter of at least 50 neurospheres was determined in control and treated cultures. Scale bar = 100 μm. (b) Bar graphs showing results as mean values ± SD of the quantification of at least three independent experiments corresponding to four different cellular pools. The left side of the image shows results for the subventricular zone (SVZ) of the brain. The right side of the image shows results for he subgranular zone of the hippocampus (SGZ). *p ≤ 0.05; **p ≤ 0.01; ***p ≤ 0.001 indicate significant results in the post-hoc pair-wise comparisons (Bonferroni) versus non-treated (basal) cultures.

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