Table 2 Single locus analysis for all the single nucleotide polymorphisms (SNPs) genotyped

From: The Gene Variants of Maternal/Fetal Renin-Angiotensin System in Preeclampsia: A Hybrid Case-Parent/Mother-Control Study

SNP

Model

Maternal

Fetal

OR

P

P*

OR

P

P *

ACE I/D

dominant

1.04 (0.73–1.48)

0.822

0.997

0.84 (0.60–1.19)

0.327

0.997

recessive

0.89 (0.60-1.33)

0.578

0.997

0.87 (0.56–1.33)

0.516

0.997

ACE G2350A

dominant

1.11 (0.79–1.55)

0.368

0.997

0.88 (0.63–1.22)

0.442

0.997

recessive

0.86 (0.52–1.43)

0.559

0.997

0.72 (0.40–1.30)

0.274

0.997

AGT M235T

dominant

1.10 (0.79–1.53)

0.651

0.997

1.40 (1.01–1.94)

0.043

0.930

recessive

0.82 (0.45–1.51)

0.455

0.997

0.98 (0.53–1.80)

0.946

1.000

AGT T174M

dominant

1.00 (0.66–1.50)

0.781

0.997

0.79 (0.51–1.23)

0.500

0.997

recessive

1.85 (0.49–6.96)

0.355

0.997

5.95 (0.66–53.56)

0.178

0.997

AT1R A1166C

dominant

-

0.505

0.997

-

0.600

0.997

 

recessive

1.05 (0.63–1.74)

1.000*

1.000

0.95 (0.54–1.67)

1.000*

1.000

  1. Statistical significance was tested at P < 0.05; OR, odds ratio; CI, confidence interval; *, using Fisher exact probability; “-” means the result could not be calculated because of limited counts; P *, corrected P-value after FDR procedure.
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