Table 5 Genetic association of the maternal and fetal genotypes (SNPs in ACE, AGT, and AT1R) with mild (m)PE and severe (s)PE.

ACE I/D

DD

reference

reference

ID

m

1.08 (0.64–1.89)

0.491

0.43 (0.18–1.03)

0.100

II

1.91 (0.32–11.44)

0.27 (0.06–1.17)

ID

s

1.07 (0.66–1.74)

0.654

1.14 (0.76–1.71)

0.054

II

1.31 (0.71–2.43)

0.65 (0.36–1.16)

ACE G2350A

AA

reference

reference

AG

m

0.96 (0.45–2.07)

0.260

0.52 (0.23–1.15)

0.215

GG

2.44 (0.75-8.01)

0.39 (0.09–1.68)

AG

s

0.95 (0.81–1.63)

0.700

0.91 (0.65–1.27)

0.354

GG

1.16 (0.65–2.05)

0.64 (0.36–1.17)

AGT M235T

TT

reference

reference

MT

m

0.74 (0.31–1.77)

0.508

1.32 (0.31–1.74)

0.477

MM

0.45 (0.39–5.44)

1.47 (0.39–5.52)

MT

s

0.94 (0.67–1.33)

0.437

1.19 (0.62–2.30)

0.004

MM

0.66 (0.35–1.32)

1.74 (1.25–2.41)

AGT T174M

TT

reference

reference

MT

m

2.00 (0.18–22.04)

0.085

1.50 (0.42–5.31)

0.442

MM

2.33 (0.60–9.02)

-

MT

s

1.60 (0.90–2.84)

0.174

0.67 (0.39–1.16)

0.283

MM

4.31 (0.43–43.69)

1.22 (0.29–5.11)

AT1R A1166C

AA

reference

reference

AC

m

1.17 (0.21–2.83)

0.928

0.76 (0.21–2.80)

0.921

CC

-

-

AC

s

1.26 (0.76–2.07)

0.545

0.67 (0.38–1.16)

0.361

CC

2.46 (0.21–29.49)

-