Table 5 Some examples of gene-gene associations that have functional association but do not have semantic similarity.

From: DES-TOMATO: A Knowledge Exploration System Focused On Tomato Species

Gene Symbol/Description

Gene Symbol/Description

Common Annotations

Reference

IAA3/ID: 543540 IAA3 protein [Solanum lycopersicum (tomato)]

EXP2/ID: 543582 expansin [Solanum lycopersicum (tomato)]

Volatile Organic Compounds (albuterol and 1,3- propanediole) were shown to promote lateral root formation that correlates with an increase in levels of EXP2 and IAA3 in the roots of tomato plants

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MAF1/ID: 543586 MFP1 attachment factor 1 [Solanum lycopersicum (tomato)]

FPP/ID: 543699 filament-like plant protein [Solanum lycopersicum (tomato)]

Filament-like plant proteins (FPP) belongs to a family of long coiled-coil proteins that interacts with the nuclear envelope-associated protein, MAF1

125

LOC543607/ID: 543607 pirin [Solanum lycopersicum (tomato)]

DAD1/ID: 543753 dad-1 protein [Solanum lycopersicum (tomato)]

Both DAD1 and pirin are mediators of programmed cell death in plants. However, DAD1 was shown to interact with BCL2 family members, while pirin plays more of a downstream role as it forms a NF-kB, BCL3, Pirin complex that is capable of modulating NF-kB-driven gene expression through interaction with an NF-kB DNA-binding site.

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