Figure 6
From: How cholesteryl ester transfer protein can also be a potential triglyceride transporter
Comparison of TG- and CE-bound CETP structures. (a) Superposition of average structures of TG bound (green) and CE bound CETP (red) obtained from respective simulation trajectories. (b) Probability distribution of bending motion exhibited by CETP when bound to TG (red) and CE (black) during UA simulations. Bending was estimated from the angle between two vectors, and as shown in the inset. The dotted line indicates the angle of bending observed in CE-CETP crystal structure. (c) Probability distribution of twisting/untwisting motion exhibited by CETP when bound to TG (red) and CE (black) during UA simulations. Twisting was computed by measuring the angle between two planes, P1 and P2 as shown in the inset. The twist angle observed in CE-CETP crystal structure is shown in dotted line for reference.
